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This work develops microfluidic technologies to advance the state-of-the-art in living cell-based assays. Current cell-based assay platforms are limited in their capabilities, particularly with respect to spatial and temporal control of external signaling factors, sample usage, and throughput. The emergence of highly quantitative, data-driven systems approaches to study....

By Edward S. Park--GIT--2011-01-20
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Repair and remodeling of bone during healing and fusion require a combination of bone resorption and formation to successfully restore the bone to its previous strength. The healing process is highly responsive to the mechanical conditions of the construct, where excessive loading can cause high strains that delay healing, but moderate loading can be beneficial. Maintai....

By Mary Katlyn Pitz--GIT--2011-01-20
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This design thesis is part of CATEAs RERC workplace accommodations grant, and it adopts a human centered design methodology to research, develop, test and evaluate designs of behind-the-counter workspaces that maximize independence and participation of employees and increase their employment possibilities. Preliminary research shows that current designs of behind-the-co....

By Gourab Kar--GIT--2011-01-20
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The main objective of this study is to develop a modeling methodology that facilitates incorporating the plant pathway into environmental contamination models recognizing the fact that plants are dynamic entities that regulate their life cycle according to natural and anthropogenic environmental conditions. A modeling framework that incorporates the plant pathway into a....

By Recep Kaya Goktas--GIT--2011-01-20
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Boron carbide (B4C) is a non-oxide ceramic in the same class of nonmetallic hard materials as silicon carbide and diamond. The high hardness, high elastic modulus and low density of B4C make it a nearly ideal material for personnel and vehicular armor. B4C plates formed via hot-pressing are currently issued to U.S. soldiers and have exhibited excellent performance; howe....

By Charles Schenck Wiley--GIT--2011-01-19
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Many scientists and engineers are turning to lab-on-a-chip systems for cheaper and high throughput analysis of chemical reactions and biomolecular interactions. In this work, we developed several lab-on-a-chip modules based on novel manipulations of individual microbeads inside microchannels. The first manipulation method employs arrays of soft ferromagnetic patterns fa....

By Zhengchun Peng--GIT--2011-01-19
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A novel video observational method for the space-time stereoscopic reconstruction of dynamic surfaces representable as graphs, such as ocean waves, is developed. Variational optimization algorithms combining image processing, computer vision and partial differential equations are designed to address the problem of the recovery of the shape of an object's surface from se....

By Guillermo Gallego Bonet--GIT--2011-01-19
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Processes at the air-water/ice interface are known to play a very important role in the release of reactive halogen species with atmospheric aerosols serving as catalysts. The ability to make different types of ice with various morphologies, hence, different adsorption and surface properties in vacuum, provide a useful way to probe the catalytic effect of ice in atmosph....

By Babajide O Olanrewaju--GIT--2011-01-19
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Horizontal-axis wind turbines operate in a complex, inherently unsteady aerodynamic environment. The flow over the blades is dominated by 3-D effects, particularly during stall, which is accompanied by massive flow separation and vortex shedding. There is always bluff-body shedding from the turbine nacelle and support structure which interacts with the rotor wake. In ad....

By Charles Eric Lynch--GIT--2011-01-19
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The objective of this research is to evaluate the stiffness and strength demands on flange braces in metal building systems. This objective is accomplished by a targeted study of the effects of various attributes of metal building systems not fully addressed in existing bracing design procedures. Special emphasis is placed on attributes such as unequal brace spacing and....

By Akhil Sharma--GIT--2011-01-19
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Quantitative relationships among processing parameters, microstructure, and material properties are of considerable interest in the context of development of robust processing routes that optimize the required material properties. As a result, the scientific literature contains a large number of experimental and theoretical studies on microstructure-properties relations....

By Ranbir Singh Jamwal--GIT--2011-01-19
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This study aims to design and implement a domain-specific computer programming language: the Building Environment Rule and Analysis (BERA) Language. As a result of the growing area of Building Information Modeling (BIM), there has been a need to develop highly customized domain-specific programming languages for handling issues in building models in the architecture, en....

By JIN KOOK LEE--GIT--2011-01-18
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