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After applying some significant performance improvements to PathCase SB and making it run faster and smoother we build a monitoring tool for the system that would facilitate future maintenance. Hence, in this thesis we propose a performance monitor specialized for the current version 4.0 of PathCase SB but that is able to automatically adapt to newer versions. The syste....

By Yves Said Azzam-EECS - Computer and Information Sciences-Case Western Reserve University / OhioLINK-masters-2012-08-24
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Research indicates Prader-Willi Syndrome (PWS) and Autistic Spectrum Disorder (ASD) have behavioral and genetic connections. Comparisons of PWS subtypes found greater autistic symptomatology in maternal uniparental disomy (mUPD) than paternal deletion (pDEL). Also, both disorders reveal social skills and facial processing deficits. This study investigated face discrimin....

By Benjamin H. Feldman-Psychology-Case Western Reserve University / OhioLINK-masters-2012-08-24
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Following the recent detection of VHSv in the Great Lakes I conducted a study on VHSv in Lake Erie yellow perch. A newly developed RT-PCR and nested-PCR assay was tested on yellow perch blood samples collected in 2008 and compared to the cell culture method of testing. I found that the RT-PCR assay coupled with the nested PCR was more sensitive in detecting VHSv in yell....

By Gregory M. Bergquist-Biology-Case Western Reserve University / OhioLINK-masters-2012-08-24
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This thesis presents computer vision algorithms and associated applications for automating cognitive and motor skill assessments. These assessments are used to diagnose cognitive and motor impairments and behavioral problems. Due to the high prevalence of such disorders and the limitation of traditional diagnosis methods, there is an urgent need for improved approaches.....

By Beatrice K. Floyd-EMC - Mechanical Engineering-Case Western Reserve University / OhioLINK-masters-2012-08-24
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We replicated a randomized clinical trial (RCT) that investigated the effectiveness of a beta-blocker therapy in reducing cardiac events among 400 patients undergoing major non-cardiac surgeries to determine if observational studies can achieve comparable results to RCTs. From the electronic medical records of Cleveland Clinic using the same inclusion criteria as the RC....

By Xuebei An-Epidemiology and Biostatistics-Case Western Reserve University / OhioLINK-masters-2012-08-24
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This thesis addresses a gap in current cognitive work on fictive motion by exploring the factors involved in the production of fictive motion rather than the standard approach of investigating fictive motion processing. Part 1 of this study consists of an experimental study of the production of coextension path fictive motion (such as the ravine ran beside the trail) in....

By Ryan Dewey-Cognitive Linguistics-Case Western Reserve University / OhioLINK-masters-2012-08-24
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In this project we propose a framework to model the behavior and evaluate the reliability and safety of robotic surgery systems. A software simulator and associated user interface tools are used to generate the simulated hardware/software data of a robotic system performing interventions on small animals. The main contributions of this work are the usage of Dynamic Baye....

By Feng Cao-EECS - Computer and Information Sciences-Case Western Reserve University / OhioLINK-masters-2012-08-24
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Many new drugs fail to pass clinical trials every year because of poor bioavailability. More than 40% of those New Chemical Entities fail to reach commercialization due to poor solubility. Nanotechnology, which can increase the active surface area, often is employed to improve the solubility of drugs. However, existing technologies using top-down approaches such as grin....

By Chien-Chih Chen-Chemistry-Case Western Reserve University / OhioLINK-masters-2012-08-24
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Background: Bisphenol-A (BPA), an industrial chemical found in plastic bottles and cans has been associated with obesity and obesity-related metabolic disturbances. However, no prior studies have examined the potential effects of BPA on the Metabolic Syndrome (MetSyn), a constellation of metabolic disturbances including dysglycemia, obesity, hypertension and dyslipidemi....

By Aiswarya Lekshmi Pillai Chandran Pillai-Epidemiology and Biostatistics-Case Western Reserve University / OhioLINK-masters-2012-08-24
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Diabetes and heart failure are common chronic conditions in the elderly. The purpose of this study is to determine if an association exists between diabetic control, as evidenced by HgbA1c levels, and the presence and type of diastolic dysfunction (DD) in patients over the age of 65 with type 2 diabetes. Patients who had an echocardiogram showing an EF over 45% were inc....

By Cristina Bocirnea-Clinical Research-Case Western Reserve University / OhioLINK-masters-2012-08-24
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Sustainability has become an important aspect of developed countries throughout the world. Sustainability is the ability to use byproducts and or waste materials from industry and recycle these materials in such a way that the application of the materials provides a beneficial use in the manufacturing or construction sector. As the United States and the rest of the worl....

By Brad A. Fronek-Fenn College of Engineering-Cleveland State University / OhioLINK-masters-2012-08-24
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Although word-finding difficulty is commonly self-reported by older adults, there are no clinical instruments able to reliably distinguish normal age-related effects from pathology in word-finding impairments. The purpose of this study is two-fold: (1) design and evaluate the validity of the Poreh Naming Test, a novel electronic confrontation naming test used to evalua....

By Orion R. Biesan-Sciences and Health Professions-Cleveland State University / OhioLINK-masters-2012-08-24
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